PROTEUS420

Cannabis ERP Software for Seed-to-Sale Operations

Run retail POS, inventory, cultivation, manufacturing, distribution, delivery, accounting, compliance and business intelligence on one connected cannabis business management platform.

  • Built for Cannabis Since 2008
  • Metrc Validated Software Provider
  • Dispensary POS + Seed-to-Sale
  • Multi-Location & Multi-State Ready
  • Real-Time Data & Reporting
  • 24/7/365 U.S.-Based Support
Cannabis flower bud close-up in a grow operation
Cured cannabis flower in a glass jar
Cannabis flower displayed on a retail counter

Cannabis ERP Explained

What Is PROTEUS420 Cannabis ERP Software?

PROTEUS420 is cannabis ERP software — an enterprise resource planning platform designed for licensed cannabis businesses. Unlike a standalone cannabis POS that focuses mainly on register transactions, PROTEUS420 connects the wider operation: inventory, purchasing, cultivation, manufacturing, distribution, delivery, e-commerce, accounting, CRM, payments, compliance reporting and business intelligence.

Cannabis ERP software gives operators one operational environment where sales, inventory, customers, financial data and regulatory workflows can stay connected. That single source of operational truth helps teams reduce reconciling between disconnected systems and make decisions from live business information.

PROTEUS420 supports seed-to-sale workflows across the cannabis supply chain while extending beyond plant and product tracking into the financial and customer side of the company.

Who We Serve

Cannabis Software for How Operators Actually Work

PROTEUS420 supports organizations across the cannabis supply chain — from a single dispensary to vertically integrated and multi-state enterprises.

Cannabis flower jars ready for dispensary retail

Dispensaries & Cannabis Retailers

Connect POS, inventory, customers, loyalty, payments, compliance, accounting, reporting and e-commerce for recreational and medical retail.

Explore dispensary POS solutions
Assorted cannabis products packaged for wholesale

Distributors & Wholesalers

Coordinate inventory, wholesale activity, transfers, fulfillment, customers and financial operations without a separate system stack.

Explore cannabis distribution software
Large-scale indoor cannabis cultivation facility

Vertically Integrated & Multi-State Operators

Connect cultivation, manufacturing, distribution and retail without forcing each business unit into a separate technology environment. PROTEUS420 supports multi-location and multi-state cannabis enterprises.

Explore cannabis ERP for complex operations

Why PROTEUS420

Built for Cannabis Operations — Not Adapted Later

PROTEUS420 has been evolving with licensed cannabis markets since 2008. The result is cannabis ERP software that treats retail POS as part of a broader operational system — inventory, finance, compliance, and growth included.

ERP Depth, Not Register-Only Software

Cannabis POS is where many platforms stop. PROTEUS420 connects register activity to inventory, purchasing, accounting, CRM, compliance reporting and business intelligence so retail is one connected surface — not a siloed app.

Explore PROTEUS420 benefits
Compliance documents and reporting

Compliance Inside Operations

Metrc and BioTrack reporting workflows in applicable markets stay tied to inventory movement and sales activity — not parked in a separate compliance tool.

Financial planning and accounting work

Financial Visibility With Ops

Cannabis accounting and financial management can live in the same ERP environment as operational activity, reducing the gap between what happened on the floor and what shows in the books.

Team collaborating as a business scales

Scales With the Business

Add locations, delivery, manufacturing or new licensed markets without rebuilding your entire technology strategy around a new stack.

AI and data intelligence visualization

PheeBee AI Intelligence

PheeBee works with each client's isolated business data to surface operational insight inside PROTEUS420 — not a generic third-party chatbot bolted on.

  • Since 2008 Cannabis technology from the start
  • Metrc Validated Software provider status
  • 24/7/365 U.S.-based support
  • People + Platform Implementation, training & ongoing help
Operator reviewing compliance and reporting documents

Compliance & State Reporting

Cannabis Compliance Software Connected to Daily Operations

Compliance shouldn't exist in a separate operational silo. PROTEUS420 supports regulated cannabis businesses with state reporting workflows and integrations, including Metrc and BioTrack, helping connect required reporting with inventory movement, sales activity and other day-to-day business operations.

Compliance requirements vary by jurisdiction. PROTEUS420 works with operators to support the requirements applicable to their licensed markets. Explore cannabis software by state, state reporting capabilities, and how Metrc integration and BioTrack workflows fit your operation.

Integrations & Partners

Connected to the Cannabis Ecosystem

Strategic integrations help PROTEUS420 connect compliance reporting, consumer discovery, payments and related cannabis services — so operators spend less time re-entering data across disconnected tools.

Compliance & Traceability

Metrc integration supports required reporting workflows in applicable regulated markets, keeping compliance connected to inventory and sales activity inside PROTEUS420.

Metrc Validated Software Provider

Menus & Consumer Discovery

Connect product and menu information with major cannabis discovery platforms so customers find accurate availability without manual menu maintenance across every channel.

Leafly · Weedmaps · Where's Weed

Payments

PROTOPay connects cannabis payment processing with PROTEUS420 retail and delivery workflows so transactions stay tied to the same operational environment as inventory and customers.

PROTOPay

Looking for partnership opportunities or want to discuss how integrations fit your stack?

Cannabis Technology Insights

What's the 411 with 420?

Practical perspective on cannabis ERP, compliance, retail operations and the technology decisions shaping licensed markets.

LATEST FROM OUR CANNABIS BUSINESS BLOG

Insights on cannabis ERP software, dispensary POS, compliance, and seed-to-sale operations.

Cannabis in Virginia: Guide to Market Entry and Compliance

Cannabis in Virginia: Guide to Market Entry and Compliance

With the seed-to-sale tracking deadline of September 1, 2026, already here, the window for a graceful entry into the Commonwealth's market i...

Sep 15, 2026
Transform Compliance with Proteus Business Solutions

Transform Compliance with Proteus Business Solutions

What if your compliance department didn't exist to chase down reporting errors, but to fuel your enterprise growth? For most operators, the ...

Aug 25, 2026
Streamline Your Dispensary with Advanced POS Solutions

Streamline Your Dispensary with Advanced POS Solutions

What if your most expensive employee isn't a person, but the data gap between your sales floor and your compliance reporting? You've like...

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FAQ

Frequently Asked Questions About Cannabis ERP Software

Clear answers about cannabis POS vs ERP, seed-to-sale tracking, Metrc compliance, pricing and the businesses PROTEUS420 supports.

What is cannabis ERP software?

Cannabis ERP software is an enterprise resource planning system designed to connect multiple areas of a cannabis business within one operational environment. Depending on the business, this can include retail POS, inventory, cultivation, manufacturing, distribution, delivery, accounting, CRM, compliance, e-commerce, payments and reporting. PROTEUS420 is cannabis ERP software built for licensed operators.

What is the difference between cannabis POS and cannabis ERP?

Cannabis POS software primarily manages retail transactions and related storefront activity. Cannabis ERP software connects those transactions with broader business functions such as inventory, purchasing, accounting, cultivation, manufacturing, distribution, delivery, CRM and reporting. PROTEUS420 includes point-of-sale capabilities as part of a broader cannabis ERP platform.

Is PROTEUS420 a seed-to-sale platform?

Yes. PROTEUS420 supports workflows across the cannabis supply chain, including cultivation, manufacturing, distribution, inventory, retail and delivery. It also extends beyond traditional seed-to-sale tracking by connecting accounting, CRM, payments, e-commerce, reporting and business intelligence.

Does PROTEUS420 integrate with Metrc?

PROTEUS420 supports Metrc integration for applicable regulated cannabis markets. Available workflows and reporting requirements depend on state regulations and licensing requirements. PROTEUS420 is a Metrc Validated Software Provider.

Does PROTEUS420 support BioTrack?

PROTEUS420 supports BioTrack reporting and integration workflows in applicable jurisdictions. Requirements vary by state and regulatory program.

Can PROTEUS420 manage multiple cannabis locations?

Yes. PROTEUS420 is designed to support businesses ranging from individual locations to multi-location and more complex cannabis enterprises, including multi-state operators.

Can PROTEUS420 support vertically integrated cannabis companies?

Yes. PROTEUS420 can connect operational functions including cultivation, manufacturing, distribution and retail within a broader ERP environment, making it suitable for vertically integrated cannabis organizations.

Does PROTEUS420 include accounting?

PROTEUS420 includes accounting and financial management capabilities designed to connect financial information with operational activity instead of relying entirely on a disconnected financial system.

Does PROTEUS420 include AI?

Yes. PheeBee is PROTEUS420's integrated AI and business intelligence environment. PheeBee is designed to work with the individual client's business information while keeping client data environments isolated from one another.

How much does PROTEUS420 cost, and how do I get started?

Pricing is tailored to your business type, size and number of locations. Visit our pricing page or request a personalized demo and our team will build a quote around your operation.

Next Step

See Your Cannabis Business on One Connected Platform

Tell us how you operate today — retail, cultivation, manufacturing, delivery or a vertically integrated model. We'll show you how PROTEUS420 cannabis ERP software can connect workflows, reduce disconnected systems and create greater visibility across your organization.

No generic sales pitch. Let's talk about your operation, your technology stack and where your cannabis business is going.