Retail that connects to everything.
Fast POS, inventory, loyalty, payments, compliance and accounting — all in one system.
Explore Retail
Cannabis Business Operating System
Run your entire cannabis business from one platform.
PROTEUS420 connects retail POS, inventory, cultivation, manufacturing, distribution, delivery, accounting, compliance and AI business intelligence — so operators stop stitching systems together.
Trusted by cannabis operators nationwide
18+ Years
Cannabis technology
24/7/365
U.S.-based support
Multi-State
Enterprise ready
Metrc + BioTrack
Compliance connectivity
One platform.
Every part of your operation.
From seed to sale, PROTEUS420 connects every part of your business on a single database.
Explore All Capabilities
Cultivation that stays connected.
Plants, batches, costs and harvests stay tied to inventory and the rest of the operation.
Explore Cultivation
Manufacturing with full traceability.
Ingredients, batches, finished goods and costing stay connected to retail and wholesale.
Explore Manufacturing
Distribution without a separate stack.
Purchasing, transfers, manifests and fulfillment stay inside the same operational system.
Explore Distribution
Delivery with the same inventory.
Orders, drivers, routes and payments stay visible outside the storefront.
Explore Delivery
E-commerce tied to live inventory.
Online menus, customers, promotions and fulfillment stay in sync with the store.
Explore E-Commerce
More Than a POS
Your POS shouldn't be the center of your technology stack.
PROTEUS420 is a true ERP — connecting every part of your business with one database, one customer record and one source of truth.
Cultivation
Track plants, batches, rooms and harvests in the same system as
retail and compliance.
Retail
Run POS, inventory, loyalty and payments connected to the rest of
your operation.
Delivery
Manage orders, drivers and routes with live inventory visibility
outside the storefront.
Compliance
Keep Metrc and BioTrack reporting tied to everyday inventory and
sales activity.
Accounting
Connect sales, COGS and financial reporting without separate
spreadsheets or systems.
Manufacturing
Trace ingredients, batches and finished goods from production to
shelf.
One database. One customer record. One inventory system. One source of truth.
PheeBee AI
Natural language. Real business intelligence.
PheeBee is PROTEUS420's AI business intelligence environment — designed to work with each client's isolated business data so operators can ask questions in plain language and get answers grounded in their own operations.
- Ask about sales, inventory, margins and trends
- Insights tied to your live operational data
- Client data environments stay isolated
- Built into PROTEUS420 — not a bolted-on chatbot
PheeBee
Business Intelligence
Which product categories lost margin last week at our downtown store?
Flower and prerolls dropped 4.2% in margin due to discount stacking on
three high-velocity SKUs. Want a breakdown by budtender and promo?
Yes — show me the promo impact.
Built to Grow With You
From your first location to your fiftieth.
The same powerful platform. At any scale.
See How It ScalesOne Location
Retail, inventory, customers, accounting and compliance in one place.
Multi-Location
Centralized products, reporting, permissions and business intelligence.
Vertically Integrated
Cultivation through manufacturing, distribution and retail without disconnected systems.
Compliance without the busywork.
Keep reporting connected to inventory, sales and your everyday operation.
Explore Compliance
Built for Compliance
Connecting a Safer Industry
- Automated reporting
- Real-time data sync
- Fewer errors
- More time for your business
Why PROTEUS420
Cannabis ERP software — not register-only POS
PROTEUS420 has been evolving with licensed cannabis markets since 2008. Retail is part of the platform, not the boundary of it.
ERP depth
Connect register activity to inventory, purchasing, accounting, CRM, compliance and business intelligence.
People + platform
Implementation, training and 24/7/365 U.S.-based support from a team that understands cannabis operations.
Technology that grows
Add locations, delivery, manufacturing or new markets without rebuilding your entire technology strategy.
AI inside the system
PheeBee works with each client's isolated business data to surface operational insight inside PROTEUS420.
Real Operators
“We needed one system that could grow with us — retail, inventory, compliance and reporting without duct-taping five tools together.”
See PROTEUS420 in action
LATEST FROM OUR CANNABIS BUSINESS BLOG
Insights on cannabis ERP software, dispensary POS, compliance, and seed-to-sale operations.
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Oct 7, 2026
Integrated Cannabis Business Solutions: 2026 Guide
Integrated Cannabis Business Solutions: A 2026 Guide to Choosing the Right System A platform can offer a long list of features and ...
Sep 28, 2026
Cannabis in Virginia: Guide to Market Entry and Compliance
With the seed-to-sale tracking deadline of September 1, 2026, already here, the window for a graceful entry into the Commonwealth's market i...
Sep 15, 2026
FAQ
Frequently asked questions about cannabis ERP
Clear answers about cannabis POS vs ERP, seed-to-sale tracking, Metrc compliance, pricing and the businesses PROTEUS420 supports.
What is cannabis ERP software?
Cannabis ERP software is an enterprise resource planning system designed to connect multiple areas of a cannabis business within one operational environment — including retail POS, inventory, cultivation, manufacturing, distribution, delivery, accounting, CRM, compliance, e-commerce, payments and reporting. PROTEUS420 is cannabis ERP software built for licensed operators.
What is the difference between cannabis POS and cannabis ERP?
Cannabis POS primarily manages retail transactions. Cannabis ERP connects those transactions with inventory, purchasing, accounting, cultivation, manufacturing, distribution, delivery, CRM and reporting. PROTEUS420 includes POS as part of a broader cannabis ERP platform.
Is PROTEUS420 a seed-to-sale platform?
Yes. PROTEUS420 supports workflows across the cannabis supply chain and extends beyond plant tracking into accounting, CRM, payments, e-commerce, reporting and business intelligence.
Does PROTEUS420 integrate with Metrc?
PROTEUS420 supports Metrc integration for applicable regulated markets and is a Metrc Validated Software Provider. Available workflows depend on state regulations and licensing requirements.
Does PROTEUS420 include AI?
Yes. PheeBee is PROTEUS420's integrated AI and business intelligence environment, designed to work with each client's isolated business data.
How do I get started?
Request a personalized demo or visit our pricing page. Pricing is tailored to business type, size and number of locations.
Ready to run your business differently?
See how PROTEUS420 connects your entire cannabis operation.
Request Your Personalized DemoNo generic sales pitch. Just your operation, your challenges, and what PROTEUS420 can do about them.
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